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GFAP Mouse mAb (SDT-2064-16)

Glial fibrillary acidic protein,GFAP

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货号 S0B3434
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产品规格
  • 宿主来源

    Mouse
  • 抗原名称

    GFAP
  • 分子别名

    Glial fibrillary acidic protein; GFAP
  • 免疫原

    Recombinant Protein
  • Accession

    P14136
  • 克隆号

    SDT-2064-16
  • 抗体类型

    Mouse mAb
  • 抗体同种型

    IgG2a,k
  • 反应种属 ?

    Hu, Ms
  • 交叉反应

    No cross-reactivity against NFL,UCHL-1, Tau-441, S100B

  • 纯化方式

    Protein A
  • 浓度

    5 mg/ml
  • 纯度

    >95%
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

    CLIA

背景介绍
  • Glial fibrillary acidic protein (GFAP) is a type of intermediate filament protein that is primarily expressed in astrocytes, which are a kind of glial cells in the central nervous system. It plays a crucial role in maintaining the structural integrity of astrocytes and providing support to neurons. GFAP helps to anchor astrocytes to the extracellular matrix and other cells, contributing to the stability of the brain tissue. Additionally, it is involved in various cellular processes such as cell signaling, migration, and proliferation of astrocytes. In clinical practice, elevated levels of GFAP in cerebrospinal fluid or blood can be an indicator of certain neurological disorders like traumatic brain injury, brain tumors, and neurodegenerative diseases, making it a potentially valuable biomarker for diagnosis and monitoring of these conditions.

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