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AACT Recombinant Rabbit mAb (SDT-897-21)

Alpha-1-antichymotrypsin,ACT,Cell growth-inhibiting gene 24/25 protein,Serpin A3,AACT,SERPINA3

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货号 S0B3417
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产品介绍

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产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    AACT

  • 分子别名

    Alpha-1-antichymotrypsin; ACT; Cell growth-inhibiting gene 24/25 protein; Serpin A3; AACT; SERPINA3

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Secreted

  • Accession

    P01011

  • 克隆号

    SDT-897-21

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

背景介绍

  • Alpha-1-antichymotrypsin (AACT), also known as SERPINA3, is a serine protease inhibitor primarily synthesized in the liver and secreted into the blood. It is an acute-phase protein involved in the inflammatory response and has a molecular weight of approximately 47.651 kDa. AACT plays a crucial role in inhibiting proteases such as cathepsin G and chymase, thereby protecting cells and tissues from proteolytic damage. Elevated levels of AACT have been observed in various diseases, including Alzheimer's disease, heart failure, and multiple cancers. Its expression and glycosylation patterns can serve as potential biomarkers for disease diagnosis and prognosis.

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