IGF-1 Recombinant Rabbit mAb (SDT-598-309)

Insulin-like growth factor 1 (IGF-1), also known as somatomedin C, is a peptide hormone composed of 70 amino acids with a molecular weight of approximately 7.6 kDa. It is primarily produced by the liver and regulated by growth hormone (GH), acting as the main mediator of GH's growth-promoting effects. IGF-1 circulates in the blood, bound to binding proteins that modulate its availability to tissues. It plays a crucial role in promoting cell growth, differentiation, and protein synthesis in various tissues, including muscle, bone, and cartilage. Additionally, IGF-1 has significant effects on brain development and is involved in the regulation of metabolism. Its levels can be used to assess GH status in medical contexts. IGF-1 is a versatile biomarker for diagnosing, monitoring, and managing endocrine (Growth Hormone Disorders), metabolic, oncological, cardiovascular, and neurological conditions. Its clinical application requires careful interpretation in context with patient-specific factors.