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Rabbit抗原名称
Amyloid beta 1-40分子别名
Aβ1-42免疫原
Synthetic PeptideAccession
P05067克隆号
SDT-1549-98抗体类型
Recombinant mAb抗体同种型
IgG应用
Sandwich ELISA反应种属 ?
Hu, Ms交叉反应
No cross-reactivity against with Amyloid beta 1-40
纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
Amyloid beta 1-42 (Aβ1-42) is a peptide composed of 42 amino acids, derived from the enzymatic cleavage of the amyloid precursor protein (APP). It is the primary component of amyloid plaques in Alzheimer's disease (AD) and is highly hydrophobic and prone to aggregation. Aβ1-42 is more likely than the more common Aβ1-40 to form toxic oligomers and fibrils, which are believed to play a key role in the pathological process of AD by disrupting neuronal function, triggering inflammatory responses, and causing synaptic dysfunction. The abnormal accumulation and aggregation of Aβ1-42 is one of the early pathological hallmarks of AD and a critical target for research and treatment of the disease.
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