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CXCL10/IP-10 Recombinant Rabbit mAb (SDT-1910-56)

10 kDa interferon gamma-induced protein (Gamma-IP10,IP-10),Small-inducible cytokine B10

价格 2,500.00 供应商现货 : 3-5个工作日
货号 S0B3373
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产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    CXCL10/IP-10
  • 分子别名

    10 kDa interferon gamma-induced protein (Gamma-IP10; IP-10), Small-inducible cytokine B10
  • 免疫原

    Recombinant Protein
  • Accession

    P02778
  • 克隆号

    SDT-1910-56
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 反应种属 ?

    Hu
  • 交叉反应

    No cross-reactivity against GRO alpha, GRO beta, MCP-1

  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 应用

    Sandwich ELISA

背景介绍
  • CXCL10, also known as interferon γ-induced protein 10 kDa (IP-10), is a cytokine belonging to the CXC chemokine family. It exerts its biological effects by binding to the CXCR3 receptor and plays a crucial role in immune responses. CXCL10 is a pleiotropic molecule with diverse functions, including promoting the chemotaxis of CXCR3+ cells, inducing apoptosis, regulating cell growth and proliferation, and modulating angiogenesis in infectious diseases, inflammation, and cancer. It is primarily produced by various cell types in response to IFN-γ and is involved in activating T lymphocytes, NK cells, macrophages, dendritic cells, and B cells. Elevated levels of CXCL10 are associated with several pathological conditions, such as autoimmune diseases, viral infections, and tumor development.

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