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Rat IL-6 Recombinant Rabbit mAb (SDT-1494-6)

货号： S0B3338

Datasheet COA
  • 价格： 询价
  • 规格：
  • 数量：
斯达特大包装询价 大包装询价

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产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    Interleukin-6 (IL-6)

  • 免疫原

    Recombinant Protein

  • Accession

    P20607

  • 克隆号

    SDT-1494-6

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 应用

    Sandwich ELISA

  • 反应种属 ?

    Rt

  • 交叉反应

    Recognizes mouse IL-6, no cross-reactivity against Rat IL-1β, IL-18, IL-2, TNF-α

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 纯度

    >95% by HPLC

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 稀释度

    [{"application": "ELISA", "dilution": "", "species": ""}, {"application": "Sandwich ELISA", "dilution": "", "species": ""}, {"application": "CLIA", "dilution": "", "species": ""}, {"application": "Lateral Flow", "dilution": "", "species": ""}, {"application": "Dot Blot", "dilution": "", "species": ""}, {"application": "WB", "dilution": "", "species": ""}, {"application": "IP", "dilution": "", "species": ""}, {"application": "IHC-P", "dilution": "", "species": ""}, {"application": "ICC", "dilution": "", "species": ""}, {"application": "IF", "dilution": "", "species": ""}, {"application": "ICFCM", "dilution": "", "species": ""}, {"application": "FCM", "dilution": "", "species": ""}, {"application": "mIHC", "dilution": "", "species": ""}]
背景介绍

  • Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory myokine is mediated through its inhibitory effects on TNF-alpha and IL-1 and its activation of IL-1ra and IL-10. IL-6 stimulates the inflammatory and auto-immune processes in many diseases such as multiple sclerosis, neuromyelitis optica spectrum disorder (NMOSD), diabetes, atherosclerosis, depression, Alzheimer's disease, systemic lupus erythematosus, multiple myeloma, prostate cancer, rheumatoid arthritis, and intracerebral hemorrhage.

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