大包装询价 产品介绍 评论(0)
宿主来源
Rabbit抗原名称
IL-4免疫原
Recombinant ProteinAccession
P05112克隆号
SDT-505-81抗体类型
Recombinant mAb抗体同种型
IgG应用
Sandwich ELISA, CLIA反应种属 ?
Hu交叉反应
Does not recognize IL-3, IL-5, IL-13, GM-CSF纯化方式
Protein A浓度
2 mg/ml纯度
>95% by HPLC标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
| 应用 | 稀释度 |
|---|---|
| Sandwich ELISA | N/A |
| CLIA | N/A |
IL-4 is a cytokine that functions as a potent regulator of immunity secreted primarily by mast cells, Th2 cells, eosinophils and basophils. IL-4 initiates signal transduction through one of two different receptor complexes, a type I receptor expressed on hematopoietic cells or a type II receptor expressed on nonhematopoietic cells. The type I receptor consists of the IL-4 R alpha and common gamma-chain/IL-2 R gamma subunits and is specific for IL-4, while the type II receptor consists of the IL-4 R alpha and IL-13 R alpha 1 subunits and can be activated by either IL-4 or IL-13. In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated.
配对推荐
评论(0)