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Rabbit抗原名称
Laminin分子别名
LN, Laminins免疫原
Recombinant Protein细胞定位
N/AAccession
P11047克隆号
SDT-148-21抗体类型
Recombinant mAb应用
Sandwich ELISA反应种属 ?
Human纯化方式
Protein A浓度
2 mg/ml纯度
>95% by HPLC性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
Laminins are heterotrimeric proteins with a high molecular mass (~400 to ~900 kDa). They contain three different chains (α, β and γ) encoded by five, four, and three paralogous genes in humans, respectively. Laminins are heterotrimeric proteins with a high molecular mass (~400 to ~900 kDa). They contain three different chains (α, β and γ) encoded by five, four, and three paralogous genes in humans, respectively. The trimeric proteins intersect to form a cross-like structure that can bind to other cell membrane and extracellular matrix molecules. The three shorter arms are particularly good at binding to other laminin molecules, which allows them to form sheets. The long arm is capable of binding to cells, which helps anchor organized tissue cells to the basement membrane. Laminin is positively correlated with the degree of liver fibrosis activity, which is significantly increased in chronic active hepatitis, cirrhosis and primary liver cancer. Laminin can also reflect the progression and severity of liver fibrosis.
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