热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 抗体 病理/IHC抗体

所有图片（1/12）

FSHR Recombinant Rabbit mAb,PBS Only (SDT-2269-36)

Follicle-stimulating hormone receptor,FSH-R,Follitropin receptor,LGR1

价格 询价 请咨询客服
货号 S0B2402p
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    FSHR

  • 分子别名

    Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; LGR1

  • 免疫原

    Synthetic Peptide

  • 细胞定位

    Cell membrane

  • Accession

    P23945

  • 克隆号

    SDT-2269-36

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Rt

  • 阳性样本

    SK-OV-3, OVCAR-3, DU 145, PC-3, mouse kidney, rat testis

  • 纯化方式

    Protein A

  • 浓度

    1mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS

  • 储存条件

    12 months from date of receipt / reconstitution, 4°C as supplied

  • 应用

    IHC-P ?

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000-1:5000 Hu, Ms, Rt
    IHC-P 1:1000 Hu, Ms, Rt
背景介绍

  • The follicle-stimulating hormone receptor (FSHR) is a 695-amino-acid, seven-transmembrane G-protein-coupled receptor expressed primarily on granulosa and Sertoli cells; upon binding FSH it activates the Gs/adenylyl cyclase/cAMP/PKA cascade to regulate steroidogenesis, gametogenesis, and reproductive tract differentiation, with naturally occurring activating or inactivating mutations causing disorders such as ovarian hyperstimulation syndrome or hypergonadotropic hypogonadism, and its extracellular domain being the target of modern infertility therapies and male contraceptive development.

  • 免疫印迹

    • WB result of FSHR Recombinant Rabbit mAb
      Primary antibody: FSHR Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: SK-OV-3 whole cell lysate 20 µg
      Lane 2: OVCAR-3 whole cell lysate 20 µg
      Lane 3: DU 145 whole cell lysate 20 µg
      Lane 4: PC-3 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 78 kDa
      Observed MW: 70 kDa

    • WB result of FSHR Recombinant Rabbit mAb
      Primary antibody: FSHR Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: mouse kidney lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 78 kDa
      Observed MW: 70 kDa

    • WB result of FSHR Recombinant Rabbit mAb
      Primary antibody: FSHR Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: rat testis lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 78 kDa
      Observed MW: 70 kDa

  • 免疫组化

    • IHC shows positive staining in paraffin-embedded human kidney. Anti-FSHR antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human ovarian cancer. Anti-FSHR antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human gastric cancer. Anti-FSHR antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • Negative control: IHC shows negative staining in paraffin-embedded human skeletal muscle. Anti-FSHR antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded mouse ovary. Anti-FSHR antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded rat ovary. Anti-FSHR antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

  • 组织表达图谱

    • Expression of FSHR in tumor tissue.

    • Expression of FSHR in human tissue.

    • Expression of FSHR in mouse & rat tissue.

评论(0)