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Rabbit抗原名称
CFTR分子别名
Cystic fibrosis transmembrane conductance regulator; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel; ABCC7免疫原
Synthetic Peptide细胞定位
Cell membrane, Endoplasmic reticulum membraneAccession
P13569克隆号
SDT-2133-154抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu阳性样本
Human pancreas纯化方式
Protein A浓度
1mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS
储存条件
12 months from date of receipt / reconstitution, 4 °C as supplied
应用
IHC-P ?
稀释度
应用 稀释度 推荐种属 IHC-P 1:250 Hu
The CFTR protein, or cystic fibrosis transmembrane conductance regulator protein, is a crucial membrane protein found primarily in epithelial cells lining various organs such as the lungs, pancreas, and sweat glands. It functions as a chloride channel, regulating the movement of chloride ions across cell membranes to maintain proper fluid balance and mucus consistency. Mutations in the CFTR gene can lead to cystic fibrosis, a genetic disorder characterized by thick, sticky mucus buildup in the lungs and digestive system, causing chronic infections and impaired organ function. The CFTR protein also plays a role in regulating sodium channels and has broader implications for epithelial cell function and ion transport.
免疫组化
IHC shows positive staining in paraffin-embedded human pancreas. Anti-CFTR antibody was used at 1/250 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
组织表达图谱
Expression of CFTR in tumor tissue.
Expression of CFTR in human tissue.







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