Mannose Receptor Recombinant Rabbit mAb， PBS Only (SDT-2206-59)
Macrophage mannose receptor 1,MMR,C-type lectin domain family 13 member D,C-type lectin domain family 13 member D-like,Human mannose receptor (hMR),Macrophage mannose receptor 1-like protein 1,CD206,CLEC13D,CLEC13DL,MRC1L1,MRC1
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宿主来源
Rabbit抗原名称
Mannose Receptor分子别名
Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human mannose receptor (hMR); Macrophage mannose receptor 1-like protein 1; CD206; CLEC13D; CLEC13DL; MRC1L1; MRC1免疫原
Synthetic Peptide细胞定位
Cell membraneAccession
P22897克隆号
SDT-2206-59抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu预测反应种属
(反应种属缩写表)Rt纯化方式
Protein A浓度
1mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS
储存条件
12 months from date of receipt / reconstitution, 4°C as supplied
应用
IHC-P ?
稀释度
应用 稀释度 推荐种属 IHC-P 1:250-1:500 Hu
The Mannose Receptor is a type of C-type lectin receptor primarily found on the surface of antigen-presenting cells such as macrophages, dendritic cells, and certain endothelial cells. It plays a crucial role in the immune system by recognizing and binding to mannose-rich glycoconjugates present on the surface of pathogens like bacteria, fungi, and viruses. Once bound, the receptor facilitates the internalization and degradation of these pathogens through endocytosis, thereby helping to clear infections and initiate immune responses. Additionally, it is involved in the clearance of apoptotic cell debris by recognizing and binding to mannose residues on glycoproteins released from dying cells. This receptor is also implicated in various inflammatory and immune-related diseases, making it an important target for therapeutic interventions.
免疫组化
IHC shows positive staining in paraffin-embedded human colon. Anti-Mannose Receptor antibody was used at 1/250 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human liver. Anti-Mannose Receptor antibody was used at 1/250 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human placenta. Anti-Mannose Receptor antibody was used at 1/250 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human spleen. Anti-Mannose Receptor antibody was used at 1/250 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human cervical squamous cell carcinoma. Anti-Mannose Receptor antibody was used at 1/250 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
组织表达图谱
Expression of Mannose Receptor in tumor tissue.
Expression of Mannose Receptor in human tissue.
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