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TFE3 Recombinant Rabbit mAb, PBS Only (SDT-760-34)

Transcription factor E3,Class E basic helix-loop-helix protein 33 (bHLHe33),BHLHE33

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货号 S0B2318P
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产品规格
  • 宿主来源

    Rabbit
  • 分子别名

    Transcription factor E3, Class E basic helix-loop-helix protein 33 (bHLHe33), BHLHE33
  • 免疫原

    Recombinant Protein
  • 细胞定位

    Cytoplasm, Nucleus
  • Accession

    P19532
  • 克隆号

    SDT-760-34
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 反应种属 ?

    Hu
  • 纯化方式

    Protein A
  • 浓度

    1 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS
  • 储存条件

    12 months from date of receipt / reconstitution,4 °C as supplied

  • 应用

    IHC-P ?

  • 稀释度

    应用 稀释度
    IHC-P 1:100
背景介绍
  • TFE3 is a member of the MiT family of the bHLH-leucine zipper transcription factor. Fusions of the TFE3 gene with several different partner genes occur in several tumours, resulting in nuclear expression of the TFE3 protein. Research studies indicate that TFE3 and other family members play roles in development, organelle biogenesis, nutrient sensing, autophagy, and energy metabolism.

  • 免疫组化

    • IHC shows positive staining in paraffin-embedded human kidney. Anti-TFE3 antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human placenta. Anti-TFE3 antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human prostate. Anti-TFE3 antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human testis. Anti-TFE3 antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human alveolar soft part sarcoma (ASPS). Anti-TFE3 antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human renal carcinomas associated with Xp11.2 translocations TFE3 gene fusions (Xp11.2 RCC). Anti-TFE3 antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

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