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ERBB3 Recombinant Rabbit mAb,PBS Only (SDT-R085)

HER3

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货号 S0B2122P
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产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    ERBB3
  • 分子别名

    HER3
  • 细胞定位

    Secreted, Cell membrane
  • Accession

    P21860
  • 克隆号

    SDT-R085
  • 抗体类型

    Rabbit mAb
  • 反应种属 ?

    Hu
  • 纯化方式

    Protein A
  • 浓度

    1 mg/ml
  • 性状

    Liquid
  • 缓冲体系

    PBS
  • 储存条件

    12 months from date of receipt, 4°C as supplied
  • 应用

    IHC-P ?

  • 稀释度

    应用 稀释度
    IHC-P 1:500-1:2000
背景介绍
  • Receptor tyrosine-protein kinase erbB-3, also known as HER3 (human epidermal growth factor receptor 3), is a membrane bound protein that in humans is encoded by the ERBB3 gene. ErbB3 is a member of the epidermal growth factor receptor (EGFR/ERBB) family of receptor tyrosine kinases. The kinase-impaired ErbB3 is known to form active heterodimers with other members of the ErbB family, most notably the ligand binding-impaired ErbB2.

  • 免疫组化

    • IHC shows positive staining in paraffin-embedded human breast cancer. Anti-ERBB3 antibody was used at 1/500 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human colon. Anti-ERBB3 antibody was used at 1/2000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

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