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宿主来源
Rabbit抗原名称
CLDN7分子别名
CEPTRL2, CPETRL2, Claudin-7, Claudin 7免疫原
Synthetic Peptide细胞定位
IntracellularAccession
O95471克隆号
SDT-077-17抗体类型
Rabbit mAb反应种属 ?
Hu, Ms纯化方式
Protein A浓度
0.5mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
IHC-P ?
稀释度
应用 稀释度 IHC-P 1:2000
Claudin is a transmembrane protein with four transmembrane domains. Claudin-7 (Cldn7) is a member of the claudin family, and its basic function is to maintain cell polarity and form tight junctions. CLDN7 has a full-length form (211 amino acids) and a C-terminal truncated form (158 amino acids). Recent studies have shown that low expression of the Cldn7 protein is found in a variety of malignant tumors, such as lung cancer, breast cancer, pancreatic cancer, and colorectal cancer (CRC).
免疫组化
IHC shows positive staining in paraffin-embedded human colon cancer.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human endometrial cancer.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human breast cancer.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human colon.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded mouse colon.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows negative staining in paraffin-embedded human renal clear cell carcinoma.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
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