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CD206 Recombinant Rabbit mAb,PBS Only (SDT-022-2)

MRC1,CLEC13D,CLEC13DL,MRC1L1

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货号 S0B2014P
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产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    CD206
  • 分子别名

    MRC1,CLEC13D, CLEC13DL, MRC1L1
  • 免疫原

    Synthetic Peptide
  • Accession

    P22897
  • 克隆号

    SDT-022-2
  • 抗体类型

    Rabbit mAb
  • 反应种属 ?

    Hu
  • 纯化方式

    Protein A
  • 研究领域

    Immunology
  • 浓度

    1 mg/ml
  • 分子量

    166kDa
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS
  • 储存条件

    12 months from date of receipt, 4°C as supplied
  • 应用

    IHC-P ?

  • 稀释度

    应用 稀释度
    IHC-P 1:4000
背景介绍
  • The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells and liver sinusoidal endothelial cells, but is also expressed on the surface of skin cells such as human dermal fibroblasts and keratinocytes.It is the first member of a family of endocytic receptors that includes Endo180 (CD280), M-type PLA2R, and DEC-205 (CD205). The receptor recognises terminal mannose, N-acetylglucosamine and fucose residues on glycans attached to proteins found on the surface of some microorganisms, playing a role in both the innate and adaptive immune systems.

  • 免疫组化

    • IHC shows positive staining in paraffin-embedded human liver kupffer cells.

      Anti-CD206 antibody was used at 1/4000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human lung.

      Anti-CD206 antibody was used at 1/4000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human lung adenocarcinoma.

      Anti-CD206 antibody was used at 1/4000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human ovarian cancer. Anti-CD206 antibody was used at 1/4000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human cervix cancer. Anti-CD206 antibody was used at 1/4000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human hepatocellular carcinoma.

      Anti-CD206 antibody was used at 1/4000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

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