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宿主来源
Armenian hamster抗原名称
Mouse TCR β分子别名
T-cell receptor beta-1 chain C region细胞定位
MembraneAccession
P01852克隆号
S-R616抗体类型
Recombinant mAb抗体同种型
IgG应用
FCM反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
50 μg/ml标记
FITC性状
Liquid缓冲体系
PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用 | 稀释度 | 推荐种属 |
---|---|---|
FCM | 5 μl per million cells in 100μl volume | Ms |
The TCR β (T-cell receptor beta chain) is a crucial component of the T-cell receptor, which, together with the TCR α chain, forms the αβTCR on the surface of T cells. This receptor is responsible for recognizing and binding to antigenic peptide complexes presented by MHC molecules. The diversity of the TCR β chain is generated through a combination of random recombination of multiple germline gene segments, gene rearrangement, junctional diversity, N-region nucleotide insertions, and random pairing of α and β chains. These mechanisms collectively provide the TCR repertoire with immense diversity, enabling T cells to recognize a wide range of antigens.
流式分析
Flow cytometric analysis of TCR β expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with SDT FITC Armenian Hamster Anti-Mouse TCR β Antibody at 0.25 μg/test and either Alexa Fluor® 647 Rat Anti-Mouse CD8a Antibody (Left panel) or Brilliant Violet 421™ Rat Anti-Mouse CD4 Antibody (Right panel). Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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