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产品规格
宿主来源
Mouse抗原名称
CD3d分子别名
T-cell surface glycoprotein CD3 delta chain; T-cell receptor T3 delta chain; T3D细胞定位
Cell membraneAccession
P04234克隆号
MEM-57抗体类型
Mouse mAb抗体同种型
IgG2a反应种属 ?
Hu阳性样本
Human PBMC纯化方式
Protein A浓度
0.2 mg/ml标记
FITC性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5 μl per million cells in 100μl volume Hu
背景介绍
CD3d, or the CD3 delta subunit of the T-cell receptor complex, is a crucial component of the T-cell receptor (TCR) complex. The TCR/CD3 complex, including CD3d, is essential for signal transduction in T-cells. When the TCR recognizes and binds to an antigen presented by MHC molecules, the CD3 complex, including CD3d, transduces the activation signal into the T-cell. Defects in the CD3d can lead to severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK), highlighting the importance of CD3d in the immune system.
流式分析
Multiparameter flow cytometric analysis of Human CD3d expression on human peripheral blood mononuclear cell populations. Human peripheral blood mononuclear cells were stained with Brilliant Violet 421™ Mouse Anti-Human CD19 antibody and either FITC Mouse IgG2a Isotype Control (Left panel) or SDT FITC Mouse Anti-Human CD3d Antibody (Right panel) at 1 μg/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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