FITC Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)
Killer cell lectin-like receptor subfamily B member 1C,CD161 antigen-like family member C,Lymphocyte antigen 55c (Ly-55c),NKR-P1.9,NKR-P1C,Natural killer cell surface protein P1-40 (NKR-P1 40),CD161c,Klrb1c
货号： S0B1657
- 价格： ￥650
- 规格：
- 数量：
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宿主来源
Rabbit抗原名称
NK1.1/CD161分子别名
Killer cell lectin-like receptor subfamily B member 1C; CD161 antigen-like family member C; Lymphocyte antigen 55c (Ly-55c); NKR-P1.9; NKR-P1C; Natural killer cell surface protein P1-40 (NKR-P1 40); CD161c; Klrb1c免疫原
Recombinant Protein细胞定位
MembraneAccession
P27814克隆号
S-428-32抗体类型
Recombinant mAb抗体同种型
IgG应用
FCM反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein A浓度
0.02mg/ml标记
FITC性状
Liquid缓冲体系
PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5 μl per million cells in 100μl volume | Ms |
CD161 is a C-type lectin-like membrane receptor expressed at high levels on NK, NKT, Th17, Mucosa Associated Invariant T cells (MAITs), non-MAIT CD8+, tissue-resident memory cells (TRMs), αβ CD4+ T cells and CD8+ T cells. CD161 levels increase when αβ T cells enter tissues. The ligand for CD161 is the lectin-like transcript 1 (LLT1). CD161/LLT1 engagement inhibits NK cell function but can inhibit or enhance αβ T cell function depending on the co-stimulatory molecules involved. The inhibitory capacity of αβ T cells can be neutralized by blocking CD161. CD161 expression on γδ T cells is associated with enhanced IFN-γ and IL-17 production and enhanced endothelial transmigration.
流式分析
Multiparameter flow cytometric analysis of Mouse NK1.1/CD161 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Phycoerythrin Rat Anti-Mouse CD49b antibody and either FITC Rabbit IgG Isotype Control (Left panel) or SDT FITC Rabbit Anti-Mouse NK1.1/CD161 antibody (Right panel) at 0.1 μg/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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