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宿主来源
Mouse抗原名称
CD8α分子别名
T-lymphocyte differentiation antigen T8/Leu-2; T-cell surface glycoprotein CD8 alpha chain; MAL; CD8a免疫原
Recombinant Protein细胞定位
Cell membraneAccession
P01732克隆号
S-1036-34抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu阳性样本
human PBMC纯化方式
Protein G浓度
0.2 mg/ml标记
PE性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μl per million cells in 100μl volume Hu
CD8A encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
流式分析
Multiparameter flow cytometric analysis of Human CD8 expression on human PBMC (human peripheral blood mononuclear cell). Human PBMC were stained with Brilliant Violet 421™ Mouse Anti-Human CD4 antibody and either Phycoerythrin Mouse IgG1, κ Isotype Control (Left panel) or SDT PE Mouse Anti-Human CD8 Antibody (Right panel) at 0.2 μg/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
引用文献(1)
- An inhalable microbe-oncolytic virus consortium for lung cancer treatment
Ling H, Yang S, Shi X, Cheng Z, Wang W, Niu M, Liu F, Sun J, Sun M.
Cell Rep Med. 2026 Apr 24 .
影响因子： 16.9
货号：S0B1634产品名称：PE Mouse Anti-Human CD8α Antibody (S-1036-34)
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