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VDAC1 Recombinant Rabbit mAb (HRP Conjugate) (SDT-R013)

Outer mitochondrial membrane protein porin 1,Plasmalemmal porin,Porin 31HL,Porin 31HM

价格 ￥720.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B1623
规格
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产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    VDAC1

  • 分子别名

    Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM

  • 细胞定位

    Mitochondrion outer membrane, Cell membrane

  • Accession

    P21796

  • 克隆号

    SDT-R013

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:5000-1:10000 Ms, Rt

  • 反应种属 ?

    Ms, Rt

  • 阳性样本

    mouse kidney, rat kidney

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    HRP

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied.
背景介绍

  • Voltage-dependent anion-selective channel 1 (VDAC-1) is a beta barrel protein that in humans is encoded by the VDAC1 gene located on chromosome 5. It forms an ion channel in the outer mitochondrial membrane (OMM) and also the outer cell membrane. In the OMM, it allows ATP to diffuse out of the mitochondria into the cytoplasm. In the cell membrane, it is involved in volume regulation. Within all eukaryotic cells, mitochondria are responsible for synthesis of ATP among other metabolite needed for cell survival. VDAC1 therefore allows for communication between the mitochondrion and the cell mediating the balance between cell metabolism and cell death. Besides metabolic permeation, VDAC1 also acts as a scaffold for proteins such as hexokinase that can in turn regulate metabolism.

  • 免疫印迹

    • WB result of VDAC1 Recombinant Rabbit mAb (HRP Conjugate)
      Lysate: mouse kidney lysate 20 µg
      Primary antibody:
      Lane 1: VDAC1 Recombinant Rabbit mAb (HRP Conjugate) at 1/5000 dilution
      Lane 2: VDAC1 Recombinant Rabbit mAb (HRP Conjugate) at 1/10000 dilution
      Lane 3: VDAC1 Recombinant Rabbit mAb (HRP Conjugate) at 1/50000 dilution
      Lane 4: VDAC1 Recombinant Rabbit mAb (HRP Conjugate) at 1/100000 dilution
      Predicted MW: 32 kDa
      Observed MW: 32 kDa

    • WB result of VDAC1 Recombinant Rabbit mAb (HRP Conjugate)
      Lysate: rat kidney lysate 20 µg
      Primary antibody:
      Lane 1: VDAC1 Recombinant Rabbit mAb (HRP Conjugate) at 1/5000 dilution
      Lane 2: VDAC1 Recombinant Rabbit mAb (HRP Conjugate) at 1/10000 dilution
      Lane 3: VDAC1 Recombinant Rabbit mAb (HRP Conjugate) at 1/50000 dilution
      Lane 4: VDAC1 Recombinant Rabbit mAb (HRP Conjugate) at 1/100000 dilution
      Predicted MW: 32 kDa
      Observed MW: 32 kDa

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