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MG53 Recombinant Rabbit mAb (S-1659-10)

Tripartite motif-containing protein 72,Mitsugumin-53 (Mg53),TRIM72

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B1487
规格
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产品介绍

产品介绍 FAQs 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    MG53

  • 分子别名

    Tripartite motif-containing protein 72; Mitsugumin-53 (Mg53); TRIM72

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Cell membrane

  • Accession

    Q6ZMU5

  • 克隆号

    S-1659-10

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Rt

  • 阳性样本

    HCT 116, mouse heart, rat heart

  • 纯化方式

    Protein A

  • 浓度

    0.5 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000-1:5000 Hu, Ms, Rt
背景介绍

  • MG53, also known as TRIM72, is a member of the TRIM protein family, primarily expressed in the heart and skeletal muscle. It consists of an N-terminal RING, B-box, and curly helix region, with a C-terminal SPRY domain. MG53 plays a crucial role in acute cell membrane repair, anti-inflammation, stem cell regeneration, and anti-virus effects. In acute cell membrane injury, MG53 oligomerizes and recruits intracellular vesicles to the injury site, forming membrane repair patches. It also inhibits the NF-κB pathway to reduce inflammation and promotes stem cell survival and regeneration. MG53 has shown therapeutic potential in myocardial infarction, acute lung injury, and other tissue injuries.

  • 免疫印迹

    • WB result of MG53 Recombinant Rabbit mAb
      Primary antibody: MG53 Recombinant Rabbit mAb at 1/5000 dilution
      Lane 1: MCF7 whole cell lysate 20 µg
      Lane 2: HCT 116 whole cell lysate 20 µg
      Negative control: MCF7 whole cell lysate
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 53 kDa
      Observed MW: 53 kDa

    • WB result of MG53 Recombinant Rabbit mAb
      Primary antibody: MG53 Recombinant Rabbit mAb at 1/5000 dilution
      Lane 1: mouse heart lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 53 kDa
      Observed MW: 53 kDa

    • WB result of MG53 Recombinant Rabbit mAb
      Primary antibody: MG53 Recombinant Rabbit mAb at 1/5000 dilution
      Lane 1: rat heart lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 53 kDa
      Observed MW: 53 kDa

FAQs

斯达特公司的抗体，可以回收利用几次？

我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定

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