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宿主来源
Rabbit抗原名称
PITPNM3分子别名
Membrane-associated phosphatidylinositol transfer protein 3; Phosphatidylinositol transfer protein; membrane-associated 3 (PITPnm 3); Pyk2 N-terminal domain-interacting receptor 1 (NIR-1); NIR1免疫原
Synthetic PeptideAccession
Q9BZ71抗体类型
Polyclonal antibody抗体同种型
IgG反应种属 ?
Hu阳性样本
MCF7, MDA-MB-231, T-47D纯化方式
Immunogen Affinity浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:1000 Hu
PITPNM3 (also known as NIR2 or PITPNM family member 3) is a membrane-associated protein belonging to the PITPNM family, playing a significant role in intracellular phosphatidylinositol transfer and signaling. This protein contains a conserved phosphatidylinositol transfer protein (PITP) domain, which enables it to bind and transfer lipid molecules such as phosphatidylinositol, thereby regulating cell membrane composition and lipid metabolism. PITPNM3 is also involved in modulating intracellular calcium homeostasis, cytoskeleton reorganization, and membrane trafficking processes, particularly in lipid exchange between the Golgi apparatus and the endoplasmic reticulum. Research indicates that PITPNM3 has critical functions in cell migration, proliferation, and differentiation, and is associated with pathological processes such as cancer and neurodegenerative diseases. Its expression and activity are regulated by multiple signaling pathways, including the PI3K/AKT and MAPK pathways, making it a potential therapeutic target.
免疫印迹
WB result of PITPNM3 Rabbit pAb
Primary antibody: PITPNM3 Rabbit pAb at 1/1000 dilution
Lane 1: MCF7 whole cell lysate 20 µg
Lane 2: MDA-MB-231 whole cell lysate 20 µg
Lane 3: T-47D whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 107 kDa
Observed MW: 107 kDa
FAQs
我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定
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