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PIK3CG Recombinant Rabbit mAb (S-1981-51)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform,PI3-kinase subunit gamma,PI3K-gamma,PI3Kgamma,PtdIns-3-kinase subunit gamma,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma (PtdIns-3-kinase subunit p110-gamma,p110gamma),Phosphoinositide-3-kinase catalytic gamma polypeptide,Serine/threonine protein kinase PIK3CG,p120-PI3K

Datasheet COA

价格￥600.00 （供应商现货： 3-5个工作日）

货号 S0B1448

规格

25μl100μl1ml

数量

产品介绍

产品介绍 FAQs 评论(0)

产品规格

宿主来源

Rabbit
抗原名称

PIK3CG
分子别名

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma (PtdIns-3-kinase subunit p110-gamma; p110gamma); Phosphoinositide-3-kinase catalytic gamma polypeptide; Serine/threonine protein kinase PIK3CG; p120-PI3K
免疫原

Synthetic Peptide
细胞定位

Cytoplasm, Cell membrane
Accession

P48736
克隆号

S-1981-51
抗体类型

Recombinant mAb
抗体同种型

IgG
反应种属 ?

Hu, Ms
阳性样本

Jurkat, K562, RAW264.7
纯化方式

Protein A
浓度

0.5 mg/ml
标记

Unconjugated
性状

Liquid
缓冲体系

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件

12 months from date of receipt / reconstitution, -20 °C as supplied
应用

WB
稀释度

应用稀释度推荐种属

WB 1:1000 Hu, Ms

应用	稀释度	推荐种属
WB	1:1000	Hu, Ms

背景介绍

PIK3CG, also known as phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, is a key component of the phosphoinositide 3-kinase (PI3K) family. It encodes a class I catalytic subunit that binds to the p85 regulatory subunit to form the PI3K complex, which catalyzes the conversion of phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), an essential step in cellular signaling. This gene is located on chromosome 7 and is highly expressed in immune cells, playing crucial roles in cell growth, survival, metabolism, and migration. Abnormal expression or mutations in PIK3CG are associated with various diseases, including immune disorders, cancers, and neurological conditions like autism. Additionally, PIK3CG has been implicated as a potential biomarker for diabetic retinopathy and a target for therapeutic interventions.

免疫印迹
- WB result of PIK3CG Recombinant Rabbit mAb
  Primary antibody: PIK3CG Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: SW480 whole cell lysate 20 µg
  Lane 2: A549 whole cell lysate 20 µg
  Lane 3: Jurkat whole cell lysate 20 µg
  Lane 4: K562 whole cell lysate 20 µg
  Negative control: SW480 whole cell lysate; A549 whole cell lysate
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 126 kDa
  Observed MW: 120 kDa
- WB result of PIK3CG Recombinant Rabbit mAb
  Primary antibody: PIK3CG Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: RAW264.7 whole cell lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 126 kDa
  Observed MW: 120 kDa