eIF2A Recombinant Rabbit mAb

CDA02,EIF-2A,MST089,MSTP004,MSTP089

价格￥600.00 （现货： 2-5个工作日）

货号 S0B1418

规格

25μl100μl1ml

数量

产品介绍

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产品规格

应用	稀释度
WB	1:500-1:1000
ICC	1:50-1:200

背景介绍

eIF2A (eukaryotic translation initiation factor 2A) is a regulatory protein involved in the initiation of protein translation, primarily functioning as an alternative translation initiation factor under stress conditions. Unlike the canonical eIF2, eIF2A does not rely on GTP or the loading of initiator tRNA. Instead, under specific conditions such as endoplasmic reticulum stress, amino acid starvation, or viral infection, it mediates non-canonical translation initiation, facilitating the translation of specific mRNAs, such as stress-related proteins or viral RNAs. The function of eIF2A is closely linked to cellular stress responses, viral infections, and tumorigenesis, although its precise mechanisms and regulatory networks require further investigation. The activity of eIF2A may provide potential therapeutic targets for certain diseases, such as cancer and neurodegenerative disorders.

免疫印迹
- WB result of eIF2A Recombinant Rabbit mAb
  Primary antibody: eIF2A Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: K562 whole cell lysate 20 µg
  Lane 2: LNCaP whole cell lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 65 kDa
  Observed MW: 65 kDa
- WB result of eIF2A Recombinant Rabbit mAb
  Primary antibody: eIF2A Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: NIH/3T3 whole cell lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 65 kDa
  Observed MW: 65 kDa
- WB result of eIF2A Recombinant Rabbit mAb
  Primary antibody: eIF2A Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: PC-12 whole cell lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 65 kDa
  Observed MW: 65 kDa
免疫细胞化学
- Immunocytochemistry analysis of eIF2A (green) in MCF-7 using eIF2A antibody,and DAPI(blue)