分享产品介绍 FAQs 评论(0)
宿主来源
Rabbit抗原名称
CD209分子别名
CD209 antigen; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1 (DC-SIGN; DC-SIGN1); CLEC4L;免疫原
Synthetic Peptide细胞定位
Cell membraneAccession
Q9NNX6克隆号
S-1776-31抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Hu纯化方式
Protein A浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 WB 1:1000 Hu
CD209, also known as DC-SIGN (Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Non-integrin), is a C-type lectin receptor primarily expressed on the surface of dendritic cells, macrophages, and certain endothelial cells. It plays a crucial role in the innate immune system by recognizing and binding to a wide range of pathogens, including viruses, bacteria, and fungi. CD209 is involved in mediating antigen endocytosis and degradation, facilitating the interaction between dendritic cells and T cells, and influencing immune responses. Additionally, it has been implicated in the binding of HIV-1 gp120, contributing to viral entry and infection. Research also suggests that CD209 may regulate macrophage polarization and neutrophil development, highlighting its importance in both innate and adaptive immunity.
免疫印迹
WB result of CD209 Recombinant Rabbit mAb
Primary antibody: CD209 gamma Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: untreated THP-1 whole cell lysate 20 µg
Lane 2: THP-1 treated with 100 ng/ml GM-CSF and 50 ng/ml hIL-4 for 7 days whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 46 kDa
Observed MW: 45~55 kDa
FAQs
我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定
评论(0)