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ANGPT2 Recombinant Rabbit mAb (S-1768-2)

Angiopoietin-2,ANG-2

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B1340
规格
数量
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产品介绍

产品介绍 FAQs 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    ANGPT2

  • 分子别名

    Angiopoietin-2; ANG-2

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Secreted

  • Accession

    O15123

  • 克隆号

    S-1768-2

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Rt

  • 阳性样本

    HepG2, HUVEC, TF-1, HeLa, mouse spleen, rat kidney

  • 预测反应种属
    (反应种属缩写表)

    Bv, Pg, Dg

  • 纯化方式

    Protein A

  • 浓度

    0.5 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000 Hu, Ms, Rt
背景介绍

  • Angiopoietin-2 (ANGPT2) is a member of the angiopoietin family and functions as a ligand for the TEK/TIE2 receptor, competing with angiopoietin-1 (ANGPT1) for binding sites. It plays a critical role in regulating angiogenesis and vascular remodeling. During embryonic development and tumorigenesis, ANGPT2 disrupts the vascular stability mediated by ANGPT1 and can induce endothelial cell apoptosis. Additionally, ANGPT2 is upregulated in various inflammatory diseases, where it contributes to the regulation of inflammation-related signaling pathways. In the tumor microenvironment, ANGPT2 synergizes with VEGF to promote endothelial cell migration and proliferation, acting as a pro-angiogenic signal. It also plays a role in lymphangiogenesis and serves as a prognostic biomarker in several cancers, including renal, liver, cervical, and gastric cancers.

  • 免疫印迹

    • WB result of ANGPT2 Recombinant Rabbit mAb
      Primary antibody: ANGPT2 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: HepG2 whole cell lysate 20 µg
      Lane 2: HUVEC whole cell lysate 20 µg
      Lane 3: TF-1 whole cell lysate 20 µg
      Lane 4: HeLa whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 57 kDa
      Observed MW: 70 kDa

    • WB result of ANGPT2 Recombinant Rabbit mAb
      Primary antibody: ANGPT2 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: mouse spleen lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 57 kDa
      Observed MW: 70 kDa

    • WB result of ANGPT2 Recombinant Rabbit mAb
      Primary antibody: ANGPT2 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: rat kidney lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 57 kDa
      Observed MW: 70 kDa

FAQs

斯达特公司的抗体，可以回收利用几次？

我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定

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