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RFC2 Recombinant Rabbit mAb (S-1276-133)

Replication factor C subunit 2,Activator 1 40 kDa subunit (A1 40 kDa subunit),Activator 1 subunit 2,Replication factor C 40 kDa subunit (RF-C 40 kDa subunit,RFC40)

Datasheet COA

价格￥600.00 （供应商现货： 3-5个工作日）

货号 S0B1281

规格

25μl100μl1ml

数量

产品介绍

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产品规格

宿主来源

Rabbit
抗原名称

RFC2
分子别名

Replication factor C subunit 2; Activator 1 40 kDa subunit (A1 40 kDa subunit); Activator 1 subunit 2; Replication factor C 40 kDa subunit (RF-C 40 kDa subunit; RFC40)
免疫原

Synthetic Peptide
细胞定位

Nucleus
Accession

P35250
克隆号

S-1276-133
抗体类型

Recombinant mAb
抗体同种型

IgG
反应种属 ?

Hu, Ms
阳性样本

HeLa, Raji, PC-3, NIH/3T3
纯化方式

Protein A
浓度

0.5 mg/ml
标记

Unconjugated
性状

Liquid
缓冲体系

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件

12 months from date of receipt / reconstitution, -20 °C as supplied
应用

WB
稀释度

应用稀释度推荐种属

WB 1:5000 Hu, Ms

应用	稀释度	推荐种属
WB	1:5000	Hu, Ms

背景介绍

RFC2 protein, or replication factor C subunit 2, is a component of the replication factor C (RFC) complex, which is essential for DNA replication. RFC2, also known as A1 or RFC40, is involved in the elongation of primed DNA templates by DNA polymerase delta and epsilon, requiring the action of accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This protein plays a role in binding ATP and may contribute to promoting cell survival. Disruption of the RFC2 gene is associated with Williams syndrome, and it has been implicated in various cancers, suggesting its potential as a prognostic marker in diseases such as liver hepatocellular carcinoma and lung adenocarcinoma. The protein is mainly localized to the nucleoplasm and, in addition, to the Golgi apparatus, indicating its involvement in intracellular processes related to DNA replication and cell proliferation.

免疫印迹
- WB result of RFC2 Recombinant Rabbit mAb
  Primary antibody: RFC2 Recombinant Rabbit mAb at 1/5000 dilution
  Lane 1: HeLa whole cell lysate 20 µg
  Lane 2: Raji whole cell lysate 20 µg
  Lane 3: PC-3 whole cell lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 39 kDa
  Observed MW: 38 kDa
- WB result of RFC2 Recombinant Rabbit mAb
  Primary antibody: RFC2 Recombinant Rabbit mAb at 1/5000 dilution
  Lane 1: NIH/3T3 whole cell lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 39 kDa
  Observed MW: 38 kDa