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CXCL10/IP-10 Rabbit Polyclonal Antibody

C-X-C motif chemokine 10,10 kDa interferon gamma-induced protein (Gamma-IP10,IP-10),Small-inducible cytokine B10,INP10,SCYB10

价格 ￥400.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B1160
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产品介绍

产品介绍 FAQs 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    CXCL10/IP-10

  • 分子别名

    C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein (Gamma-IP10; IP-10); Small-inducible cytokine B10; INP10; SCYB10

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Secreted

  • Accession

    P02778

  • 抗体类型

    Polyclonal antibody

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu

  • 纯化方式

    Immunogen Affinity

  • 浓度

    0.5 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000 Hu
背景介绍

  • CXCL10, also known as Interferon-gamma-induced protein 10 (IP-10), is a small molecular weight cytokine belonging to the CXC chemokine family. It is a pleiotropic molecule with multiple functions, including the ability to exert potent biological effects such as promoting chemotaxis of CXCR3+ cells, inducing apoptosis, regulating cell growth and proliferation, and angiogenesis in infectious and inflammatory diseases and cancer. The involvement of CXCL10 and its receptor CXCR3 in the pathogenesis of many autoimmune diseases has been established, including organ-specific diseases (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease) and systemic diseases (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus). The role of CXCL10 in kidney diseases suggests that it is involved in the development of kidney diseases through the chemoattraction of inflammatory cells, promotion of cell growth, and vascular inhibition. Additionally, CXCL10 has been shown to be an important biomarker for disease severity and can serve as a prognostic indicator for various kidney diseases. CXCL10 is also associated with the occurrence, development, therapeutic efficacy, and prognosis of various tumors.

  • 免疫印迹

    • WB result of CXCL10/IP-10 Rabbit pAb
      Primary antibody: CXCL10/IP-10 Rabbit pAb at 1/1000 dilution
      Lane 1: untreated THP-1 whole cell lysate 20 µg
      Lane 2: THP-1 treated with 100 ng/ml PMA for 24 hours, then 10 pg/ml LPS for 24 hours and 20ng/ml IFN-γ for 24 hours, and 300ng/ml Brefeldin A for the last 4 hours whole cell lysate 20 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 11 kDa
      Observed MW: 12 kDa

FAQs

斯达特公司的抗体，可以回收利用几次？

我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定

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