p44/42 MAPK (Erk1/2) Rabbit Polyclonal Antibody
erk1,MK03,MAPK3,ERK1,PRKM3ERK1,PRKM3,Mitogen-activated protein kinase 3,MAP kinase 3,MAPK 3,ERT2,Extracellular signal-regulated kinase 1,ERK-1,Insulin-stimulated MAP2 kinase,MAP kinase isoform p44,p44-MAPK,Microtubule-associated protein 2 kinase,p44-ERK1,Mitogen-activated protein kinase 1,MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2 (ERK-2),MAP kinase isoform p42 (p42-MAPK),Mitogen-activated protein kinase 2 (MAP kinase 2,MAPK 2),PRKM1,PRKM2
货号： S0B1145
- 价格： ￥400
- 规格：
- 数量：
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别名
erk1,MK03,MAPK3,ERK1,PRKM3ERK1,PRKM3,Mitogen-activated protein kinase 3,MAP kinase 3,MAPK 3,ERT2,Extracellular signal-regulated kinase 1,ERK-1,Insulin-stimulated MAP2 kinase,MAP kinase isoform p44,p44-MAPK,Microtubule-associated protein 2 kinase,p44-ERK1,Mitogen-activated protein kinase 1,MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2 (ERK-2),MAP kinase isoform p42 (p42-MAPK),Mitogen-activated protein kinase 2 (MAP kinase 2,MAPK 2),PRKM1,PRKM2宿主来源
Rabbit抗原名称
p44/42 MAPK (Erk1/2)免疫原
Synthetic PeptideAccession
P28482抗体类型
Polyclonal antibody抗体同种型
IgG应用
WB反应种属 ?
Ms, Rt阳性样本
Mouse brain, rat brain纯化方式
Immunogen Affinity浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:5000 | Ms, Rt |
p44/42 MAPK, also known as extracellular signal-regulated kinases 1 and 2 (ERK1/2), are a subfamily of the mitogen-activated protein kinases (MAPK) family. They are activated by a wide range of extracellular stimuli, including growth factors, cytokines, and environmental stress signals. The activation of p44/42 MAPK involves a cascade of phosphorylation events, starting from MAPK kinase kinase (MAPKKK), through MAPK kinase (MAPKK), and finally leading to the activation of p44/42 MAPK. Upon activation, p44/42 MAPK phosphorylate and activate specific MAPK-activated protein kinases (MAPKAPKs), such as members of the RSK, MSK, or MNK families, as well as MK2/3/5. These kinases further amplify the signal and mediate the biological processes regulated by different MAPKs. Mutations or dysregulation of the p44/42 MAPK pathway have been implicated in various diseases, including cancer, neurological disorders, and cardiovascular diseases.
免疫印迹
WB result of p44/42 MAPK (Erk1/2) Rabbit pAb
Primary antibody: p44/42 MAPK (Erk1/2) Rabbit pAb at 1/5000 dilution
Lane 1: mouse brain lysate 20 µg
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 41 kDa
Observed MW: 38, 42 kDaWB result of p44/42 MAPK (Erk1/2) Rabbit pAb
Primary antibody: p44/42 MAPK (Erk1/2) Rabbit pAb at 1/5000 dilution
Lane 1: rat brain lysate 20 µg
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 41 kDa
Observed MW: 38, 42 kDa
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