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Invivo anti-Mouse CD8α Recombinant mAb STAR

Lyt-2

价格 ￥700.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B1141
规格
数量
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产品介绍 评论(0)

产品规格

  • 宿主来源

    Rat

  • 抗原名称

    CD8α

  • 分子别名

    Lyt-2

  • 细胞定位

    Cell membrane

  • Accession

    P01731

  • 克隆号

    53-6.7

  • 抗体类型

    Rat mAb

  • 抗体同种型

    Rat IgG2a,k

  • 同型对照

    Invivo rat IgG2a isotype control, anti-trinitrophenol

  • 推荐稀释液

    S0D0023

  • 反应种属 ?

    Ms

  • 纯化方式

    Protein G

  • 浓度

    5 mg/ml

  • 纯度

    >95% (Determined by SDS-PAGE)

  • 内毒素含量

    <2EU/mg

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, containing no preservative

  • 储存条件

    2 to 8 °C for 2 weeks under sterile conditions;
    -20 °C for 3 months under sterile conditions;
    -80 °C for 24 months under sterile conditions.
    Please avoid repeated freeze-thaw cycles.

  • 应用

    in vivo CD8+ T cell depletion

  • 稀释度

    • 稀释度

      [{"application": "ELISA", "dilution": "", "species": ""}, {"application": "Sandwich ELISA", "dilution": "", "species": ""}, {"application": "CLIA", "dilution": "", "species": ""}, {"application": "Lateral Flow", "dilution": "", "species": ""}, {"application": "Dot Blot", "dilution": "", "species": ""}, {"application": "WB", "dilution": "", "species": ""}, {"application": "IP", "dilution": "", "species": ""}, {"application": "IHC-P", "dilution": "", "species": ""}, {"application": "ICC", "dilution": "", "species": ""}, {"application": "IF", "dilution": "", "species": ""}, {"application": "mIHC", "dilution": "", "species": ""}, {"application": "ChIP", "dilution": "", "species": ""}]
背景介绍

  • CD8α encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

  • 验证数据

    • CD8+T cell depletion efficacy of S0B1141 in C57 mice

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