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宿主来源
Rabbit抗原名称
VEGF Receptor/FLK-1分子别名
Vascular endothelial growth factor receptor 2; VEGFR-2; Fetal liver kinase 1 (FLK-1); Kinase insert domain receptor (KDR); Protein-tyrosine kinase receptor flk-1; CD309; KDR免疫原
Recombinant Protein细胞定位
Cell junction, Cell membraneAccession
P35968克隆号
S-1519-34抗体类型
Recombinant mAb抗体同种型
IgG应用
WB反应种属 ?
Hu阳性样本
HUVEC预测反应种属
(反应种属缩写表)P. paniscus, P. troglodytes纯化方式
Protein A浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Hu |
VEGF Receptor 2 (VEGFR2), also known as kinase insert domain receptor (KDR) in humans, is a crucial tyrosine kinase receptor involved in angiogenesis, the formation of new blood vessels. It plays a significant role in various physiological and pathological processes, including development, wound healing, and tumor growth. VEGFR2 is activated upon binding to VEGF (Vascular Endothelial Growth Factor), leading to a series of downstream signaling events that promote endothelial cell proliferation, migration, and survival. This receptor is composed of an extracellular ligand-binding domain, a transmembrane domain, and an intracellular tyrosine kinase domain. Upon VEGF binding, VEGFR2 undergoes dimerization and autophosphorylation, which activates various signaling pathways such as PI3K/Akt, MAPK/ERK, and others.
免疫印迹
WB result of VEGF Receptor 2/FLK-1 Recombinant Rabbit mAb
Primary antibody: VEGF Receptor 2/FLK-1 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: HeLa whole cell lysate 20 µg
Lane 2: HUVEC whole cell lysate 20 µg
Negative control: HeLa whole cell lysate
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 152 kDa
Observed MW: 200~260 kDa
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