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IL-13RA2/CD213a2 Rabbit Polyclonal Antibody

Interleukin-13 receptor subunit alpha-2,IL-13 receptor subunit alpha-2,IL-13R subunit alpha-2,IL-13R-alpha-2,Interleukin-13-binding protein

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B1131
规格
数量
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产品介绍

产品介绍 FAQs 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    IL-13RA2/CD213a2

  • 分子别名

    Interleukin-13 receptor subunit alpha-2; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; Interleukin-13-binding protein

  • 免疫原

    Recombinant Protein

  • 细胞定位

    Cell membrane

  • Accession

    Q14627

  • 抗体类型

    Polyclonal antibody

  • 抗体同种型

    IgG

  • 反应种属 ?

    Hu, Ms, Rt

  • 阳性样本

    A375, U-87, HeLa, mouse testis, rat testis

  • 纯化方式

    Immunogen Affinity

  • 浓度

    0.5 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000 Hu, Ms, Rt
背景介绍

  • IL-13RA2, or Interleukin 13 Receptor Alpha 2, is a protein that has gained significant attention for its role in cancer and as a potential therapeutic target. IL-13RA2 is overexpressed in various cancers, including melanoma, renal cell carcinoma, adrenocortical carcinoma, and several brain tumors. Its expression is associated with tumor invasion, metastasis, and poor prognosis. Unlike the IL-13Rα1, which activates the JAK/STAT pathway, IL-13RA2 was considered a non-signaling receptor due to its short intracellular domain. However, it has been shown to participate in signaling pathways that promote tumor progression, such as those involving AP-1 and ERK.

  • 免疫印迹

    • WB result of IL-13RA2/CD213a2 Rabbit pAb
      Primary antibody: IL-13RA2/CD213a2 Rabbit pAb at 1/1000 dilution
      Lane 1: Daudi whole cell lysate 20 µg
      Lane 2: A375 whole cell lysate 20 µg
      Lane 3: U-87 MG whole cell lysate 20 µg
      Lane 4: HeLa whole cell lysate 20 µg
      Negative control: Daudi whole cell lysate
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 44 kDa
      Observed MW: 70 kDa

    • WB result of IL-13RA2/CD213a2 Rabbit pAb
      Primary antibody: IL-13RA2/CD213a2 Rabbit pAb at 1/1000 dilution
      Lane 1: mouse testis lysate 20 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 44 kDa
      Observed MW: 70 kDa

    • WB result of IL-13RA2/CD213a2 Rabbit pAb
      Primary antibody: IL-13RA2/CD213a2 Rabbit pAb at 1/1000 dilution
      Lane 1: rat testis lysate 20 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 44 kDa
      Observed MW: 70 kDa

FAQs

斯达特公司的抗体，可以回收利用几次？

我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，我们对一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定

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