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宿主来源
Armenian hamster抗原名称
IL-1β分子别名
Interleukin-1 beta; IL-1 beta细胞定位
SecretedAccession
P10749, Q63264克隆号
S-R479抗体类型
Armenian hamster mAb抗体同种型
IgG应用
in vivo IL-1β neutralization, in vitro IL-1β neutralization, WB反应种属 ?
Ms, Rt纯化方式
Protein G浓度
5 mg/ml内毒素含量
<2EU/mg标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, containing no preservative
储存条件
2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Ms, Rt |
IL-1β (Interleukin-1 beta) is a crucial pro-inflammatory cytokine primarily produced by activated monocytes and macrophages, but it can also be expressed in various cell types, including epithelial cells, endothelial cells, fibroblasts, synovial cells, neurons, mast cells, and glial cells. The biological functions of IL-1β are extensive, and it is involved in various autoimmune inflammatory responses and cellular activities, including cell proliferation, differentiation, and apoptosis. It also participates in the regulation of IL-6 and TNF-α and activates vascular adhesion molecules such as ICAM1. IL-1β plays a key role in the acute-phase response, including fever, acute protein synthesis, anorexia, and somnolence.
免疫印迹
WB result of Invivo anti-mouse/rat IL-1β Recombinant Rabbit mAb
Primary antibody: Invivo anti-mouse/rat IL-1β Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: IL-1β Protein, Mouse 10 ng
Lane 2: IL-1β Protein, Rat 10 ng
Secondary antibody: Goat Anti-Armenian Hamste IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 31 kDa
Observed MW: 16 kDa
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