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宿主来源
Mouse抗原名称
CD40分子别名
B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40细胞定位
Secreted, Cell membraneAccession
P25942克隆号
S-R530抗体类型
Mouse mAb抗体同种型
IgG2b应用
FCM反应种属 ?
Hu阳性样本
human PBMC纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4储存条件
12 months from date of receipt / reconstitution, 2-8 °C as supplied.
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 1:2000 | Hu |
The CD40 is a type I transgender protein that is transmitted in the immune system's B cells and special antigen to the surface of the cells and many non -hematopoietic cell types and cancer cells. It belongs to the TNF receptor super family.CD40 is expressed in B cells, foam dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. CD40 interacts with CD40 Ligand (CD40L/TNFSF5).CD40/CD40L is essential for the beginning and progress of cells and body fluid adaptive immunity, and it is an important area of concern in the study of tumor immunology, neurodegeneration, vascular disease and inflammatory diseases.
流式分析
Flow cytometric analysis of human PBMC (human peripheral blood mononuclear cell) labelling Human CD40 antibody at 1/2000 (0.1 μg) dilution (Right) compared with a Mouse monoclonal IgG isotype control (Left). Goat Anti - Mouse IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD19 - Brilliant Violet 421™ separately. Events were gated on viable lymphocytes.
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