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BRCA2 Recombinant Rabbit mAb (S-1485-4)

Breast cancer type 2 susceptibility protein,Fanconi anemia group D1 protein,FACD,FANCD1

价格 400.00 供应商现货 : 3-5个工作日
货号 S0B0989
规格
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产品介绍 FAQs 评论(0)

产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    BRCA2
  • 分子别名

    Breast cancer type 2 susceptibility protein, Fanconi anemia group D1 protein, FACD, FANCD1
  • 免疫原

    Recombinant Protein
  • 细胞定位

    Cytoplasm, Nucleus
  • Accession

    P51587
  • 克隆号

    S-1485-4
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 反应种属 ?

    Hu
  • 阳性样本

    HeLa, MDA-MB-231
  • 纯化方式

    Protein A
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB
  • 稀释度

    应用 稀释度 推荐种属
    WB 1:1000 Hu
背景介绍
  • The BRCA2 protein is a crucial component in maintaining genomic stability and is involved in various cellular functions such as homologous recombination, G2 checkpoint control, and protection of stalled replication forks. BRCA2 is also known to interact with numerous other proteins and has roles in DNA replication, including stabilizing stalled replication forks and protecting them from degradation. Mutations in the BRCA2 gene can lead to a deficiency in these repair mechanisms, which is why individuals with BRCA2 mutations are at an increased risk for developing certain types of cancer, particularly breast and ovarian cancer.

  • 免疫印迹

    • WB result of BRCA2 Recombinant Rabbit mAb
      Primary antibody: BRCA2 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: HeLa whole cell lysate 20 µg
      Lane 2: MDA-MB-231 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 384 kDa
      Observed MW: 280 kDa

FAQs

斯达特公司的抗体,可以回收利用几次?

我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变,不同客户在回收抗体的保存条件上也会有差异,所以抗体回收使用效果无法保证。另外,我们对一批抗体回收验证测试,测试结果显示不同抗体可回收次数不同,一般效价越高的抗体,可重复使用的次数越多,客户可根据实验情况来确定

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