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Rabbit抗原名称
BRCA2分子别名
Breast cancer type 2 susceptibility protein, Fanconi anemia group D1 protein, FACD, FANCD1免疫原
Recombinant Protein细胞定位
Cytoplasm, NucleusAccession
P51587克隆号
S-1485-4抗体类型
Recombinant mAb抗体同种型
IgG应用
WB反应种属 ?
Hu阳性样本
HeLa, MDA-MB-231纯化方式
Protein A浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Hu |
The BRCA2 protein is a crucial component in maintaining genomic stability and is involved in various cellular functions such as homologous recombination, G2 checkpoint control, and protection of stalled replication forks. BRCA2 is also known to interact with numerous other proteins and has roles in DNA replication, including stabilizing stalled replication forks and protecting them from degradation. Mutations in the BRCA2 gene can lead to a deficiency in these repair mechanisms, which is why individuals with BRCA2 mutations are at an increased risk for developing certain types of cancer, particularly breast and ovarian cancer.
免疫印迹
WB result of BRCA2 Recombinant Rabbit mAb
Primary antibody: BRCA2 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: HeLa whole cell lysate 20 µg
Lane 2: MDA-MB-231 whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 384 kDa
Observed MW: 280 kDa
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