5-HT (Serotonin) Transporter Recombinant Rabbit mAb (S-1332-21)

Sodium-dependent serotonin transporter,SERT,5HT transporter (5HTT),Solute carrier family 6 member 4,SLC6A4,HTT

Datasheet COA

价格￥600.00 （供应商现货： 3-5个工作日）

货号 S0B0969

规格

25μl100μl1ml

数量

产品介绍

产品介绍 FAQs 评论(0)

产品规格

宿主来源

Rabbit
抗原名称

5-HT (Serotonin) Transporter
分子别名

Sodium-dependent serotonin transporter, SERT, 5HT transporter (5HTT), Solute carrier family 6 member 4, SLC6A4, HTT
免疫原

Synthetic Peptide
细胞定位

Cell membrane
Accession

Q60857
克隆号

S-1332-21
抗体类型

Recombinant mAb
抗体同种型

IgG
反应种属 ?

Hu, Ms
预测反应种属
(反应种属缩写表)

Mq
纯化方式

Protein A
浓度

0.5 mg/ml
标记

Unconjugated
性状

Liquid
缓冲体系

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件

12 months from date of receipt / reconstitution, -20 °C as supplied
应用

IHC-P ? ,
WB
稀释度

应用稀释度推荐种属

WB 1:500-1:1000 Ms
IHC-P 1:100-1:200 Hu, Ms

应用	稀释度	推荐种属
WB	1:500-1:1000	Ms
IHC-P	1:100-1:200	Hu, Ms

背景介绍

The Sodium-dependent serotonin transporter, also known as SERT, is a protein that transports serotonin, a neurotransmitter, across the cell membrane. It plays a crucial role in the regulation of mood, anxiety, and other brain functions. SERT is the target for selective serotonin reuptake inhibitors (SSRIs), which are commonly prescribed antidepressant medications. SERT is part of the neurotransmitter sodium symporter (NSS) family and functions by binding to serotonin and sodium ions to facilitate the transport of serotonin from the synaptic cleft back into the presynaptic neuron, terminating the signal. The transporter undergoes a series of conformational changes that allow it to bind to serotonin and sodium ions and then release them on the other side of the cell membrane.

免疫印迹
- WB result of 5-HT (Serotonin) Transporter Recombinant Rabbit mAb
  Primary antibody: 5-HT (Serotonin) Transporter Recombinant Rabbit mAb at 1/1000 dilution
  Lane 1: untreated mouse platelet lysate 20 µg
  Lane 2: mouse platelet treated with PNase F lysate 20 µg
  Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Predicted MW: 70 kDa
  Observed MW: 50~250 kDa
  This blot was developed with high sensitivity substrate
免疫组化
- IHC shows positive staining in paraffin-embedded human cerebral cortex. Anti- 5-HT (Serotonin) Transporter antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
- IHC shows positive staining in paraffin-embedded mouse cerebral cortex. Anti- 5-HT (Serotonin) Transporter antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
- IHC shows positive staining in paraffin-embedded mouse spleen. Anti- 5-HT (Serotonin) Transporter antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.