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产品中心 抗体 功能性抗体

Invivo anti-mouse Ly6G/Ly6C (Gr-1)

Lymphocyte antigen 6G,Ly-6G.1

价格 ￥700.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B0838
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产品介绍 评论(0)

产品规格

  • 宿主来源

    Rat

  • 抗原名称

    mouse Ly-6G/Ly-6C (Gr-1)

  • 分子别名

    Lymphocyte antigen 6G, Ly-6G.1

  • 细胞定位

    Cell membrane

  • Accession

    P35461

  • 克隆号

    S-R425

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    Rat IgG2b,k

  • 反应种属 ?

    Ms

  • 纯化方式

    Protein G

  • 浓度

    5 mg/ml

  • 纯度

    >95% (Determined by SDS-PAGE)

  • 内毒素含量

    <1EU/mg

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, containing no preservative

  • 储存条件

    2 to 8 °C for 2 weeks under sterile conditions;

    -20 °C for 3 months under sterile conditions;

    -80 °C for 24 months under sterile conditions.

    Please avoid repeated freeze-thaw cycles.

  • 应用

    in vivo depletion of Gr-1+ myeloid cells
背景介绍

  • This antibody recognizes the same epitope as clone RB6-8C5.It recognizes strongly with mouse Ly6G and weakly with mouse Ly6C. Ly-6G protein is a GPI (glycosylphosphatidylinositol)-anchored protein. Ly6G is primarily expressed on monocytes, neutrophils, and T cells. It plays a crucial role in inhibiting antitumor efficacy and Tcell responses. Due to its specific expression on neutrophils, Ly6G has been widely used as a surface marker in flow cytometry, cell sorting, and immune phenotyping experiments. Unique expression of Ly6G in bone marrow indicates its involvement in hematopoietic microenvironment, potentially regulating the development or function of immune cells within the bone marrow niche.

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