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Rat抗原名称
mouse Ly-6G/Ly-6C (Gr-1)分子别名
Lymphocyte antigen 6G, Ly-6G.1细胞定位
Cell membraneAccession
P35461克隆号
S-R425抗体类型
Recombinant mAb抗体同种型
Rat IgG2b,k应用
in vivo depletion of Gr-1+ myeloid cells反应种属 ?
Ms纯化方式
Protein G浓度
5 mg/ml内毒素含量
<1EU/mg标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, containing no preservative
储存条件
2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.
This antibody recognizes the same epitope as clone RB6-8C5.It recognizes strongly with mouse Ly6G and weakly with mouse Ly6C. Ly-6G protein is a GPI (glycosylphosphatidylinositol)-anchored protein. Ly6G is primarily expressed on monocytes, neutrophils, and T cells. It plays a crucial role in inhibiting antitumor efficacy and Tcell responses. Due to its specific expression on neutrophils, Ly6G has been widely used as a surface marker in flow cytometry, cell sorting, and immune phenotyping experiments. Unique expression of Ly6G in bone marrow indicates its involvement in hematopoietic microenvironment, potentially regulating the development or function of immune cells within the bone marrow niche.
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