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CNPase Rabbit polyclonal antibody

2',3'-cyclic-nucleotide 3'-phosphodiesterase,CNP

价格 400.00 供应商现货 : 3-5个工作日
货号 S0B0806
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产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    CNPase
  • 分子别名

    2',3'-cyclic-nucleotide 3'-phosphodiesterase, CNP
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Melanosome, Membrane
  • Accession

    P09543
  • 抗体类型

    Polyclonal antibody
  • 抗体同种型

    IgG
  • 反应种属 ?

    Ms, Rt
  • 预测反应种属
    (反应种属缩写表)

    Or, Hs
  • 纯化方式

    Immunogen Affinity
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

  • 应用

    WB

  • 稀释度

    应用 稀释度
    WB 1:1000
背景介绍
  • CNPase is a myelin-associated enzyme that makes up 4% of total CNS myelin protein, and is thought to undergo significant age-associated changes. It is named for its ability to catalyze the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. CNPase is expressed exclusively by oligodendrocytes in the CNS, and the appearance of CNPase seems to be one of the earliest events of oligodendrocyte differentiation. CNPase is thought to play a critical role in the events leading up to myelination. CNPase also associates with microtubules in brain tissue and FRTL-5 thyroid cells, and is reported to have microtubule-associated protein-like activity, being able to catalyze microtubule formation at low molar ratios. Deletion of the C-terminus of CNPase or phosphorylation abolish the catalytic activity of microtubule formation. CNPase can link tubulin to cellular membranes, and might be involved in the regulation cytoplasmic microtubule distribution.

  • 免疫印迹

    • WB result of CNPase Rabbit pAb
      Primary antibody: CNPase Rabbit pAb at 1/1000 dilution
      Lane 1: mouse brain lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 48 kDa
      Observed MW: 48 kDa

    • WB result of CNPase Rabbit pAb
      Primary antibody: CNPase Rabbit pAb at 1/1000 dilution
      Lane 1: rat brain lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 48 kDa
      Observed MW: 48 kDa

FAQs

斯达特公司的抗体,可以回收利用几次?

我们一般不推荐客户回收利用抗体。 因为抗体使用之后缓冲体系已经发生改变,不同客户在回收抗体的保存条件上也会有差异,所以抗体回收使用效果无法保证。另外,我们对一批抗体回收验证测试,测试结果显示不同抗体可回收次数不同,一般效价越高的抗体,可重复使用的次数越多,客户可根据实验情况来确定

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