分享产品介绍 评论(0)
宿主来源
Mouse抗原名称
CD42b分子别名
GPIb, Platelet glycoprotein Ib alpha chain, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha免疫原
Recombinant Protein细胞定位
MembraneAccession
P07359克隆号
S-935-7抗体类型
Mouse mAb抗体同种型
IgG1,k反应种属 ?
Hu纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied.应用
FCM
稀释度
应用 稀释度 FCM 1:2000
Platelet glycoprotein Ib alpha chain also known as glycoprotein Ib (platelet), alpha polypeptide or CD42b (Cluster of Differentiation 42b), is a protein that in humans is encoded by the GP1BA gene. Glycoprotein Ib (GPIb) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The GpIb functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V to form the glycoprotein Ib-IX-V complex. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis.
流式分析
Flow cytometric analysis of human PBMC (human peripheral blood mononuclear cell) labelling CD42b antibody at 1/2000 (0.1 μg) dilution (Right) compared with a Mouse monoclonal IgG isotype control (Left). Goat Anti - Mouse IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD41 (APC conjugate) separately. Events were gated on viable cells.
评论(0)