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产品中心 抗体 Biosimilar抗体

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Anti-PD-1 Monoclonal Antibody (Pembrolizumab)

价格 ￥2,500.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B0567
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Human

  • 抗原名称

    PD-1

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG4,k

  • 反应种属 ?

    Hu

  • 纯化方式

    Protein A

  • 浓度

    5 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, containing no preservative. Endotoxin level is ≤ 1 EU/mg

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    Blocking of PD-1/PD-L1 signaling Functional assays

背景介绍

  • Pembrolizumab is a humanized monoclonal IgG4 kappa antibody directed against human cell surface PD-1 (programmed death receptor-1) on lymphocytes. The PD-1 receptor provides an important “immune checkpoint,” which helps prevent the immune system from attacking itself.

  • 验证数据

    • Immobilized PD-1 His Tag Protein, Human(UA010004) can bind Pembrolizumab. The EC50 for this effect is 13.74 ng/mL.

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