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产品规格
宿主来源
Human克隆号
S-SC006抗体类型
Recombinant mAb纯化方式
Protein G浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, containing no preservative.
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
Blocking of TGFβ signaling Functional assays
稀释度
应用 稀释度 ELISA 12.64-10000 ng/ml
背景介绍
Fresolimumab is a human monoclonal antibody and an immunomodulator. It is intended for the treatment of idiopathic pulmonary fibrosis (IPF), focal segmental glomerulosclerosis, and cancer (kidney cancer and melanoma). It binds to and inhibits all isoforms of the protein transforming growth factor beta (TGF-β).
ELISA
Immobilized TGF-β1 Protein, Human(UA040085) can bind Fresolimumab. The EC50 for this effect is 48.42 ng/mL.
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