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产品中心 抗体 Biosimilar抗体

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Anti-CD124 Monoclonal Antibody(Dupilumab)

Interleukin-4 receptor subunit alpha,IL-4 receptor subunit alpha,IL-4R subunit alpha,IL-4R-alpha,IL-4RA,CD124

价格 ￥1,800.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B0560
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数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Human

  • 分子别名

    Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD124

  • Accession

    P24394

  • 克隆号

    S-SC022

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG4,k

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 内毒素含量

    <1EU/mg

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, containing no preservative

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    Blocking of IL-4Rα signaling Functional assays

  • 稀释度

    应用 稀释度
    ELISA 1.221-5000 ng/ml
背景介绍

  • Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis.

  • ELISA

    • Immobilized IL-4R alpha/CD124 His Tag Protein, Human(UA010382) can bind Dupilumab. The EC50 for this effect is 63.35 ng/mL.

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