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产品规格
宿主来源
Human分子别名
Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD124Accession
P24394克隆号
S-SC022抗体类型
Recombinant mAb抗体同种型
IgG4,k应用
Blocking of IL-4Rα signaling Functional assays纯化方式
Protein A浓度
2 mg/ml内毒素含量
<1EU/mg标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, containing no preservative储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
稀释度
应用 | 稀释度 |
---|---|
ELISA | 1.221-5000 ng/ml |
背景介绍
Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis.
ELISA
Immobilized human IL-4Rα at 0.5 μg/ml (50 μL/well) can bind to Dupilumab with a linear range of 1.221 ng/ml-5 μg/ml.
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