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产品中心 抗体 Biosimilar抗体

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Anti-CD254 Monoclonal Antibody(Denosumab)

Tumor necrosis factor ligand superfamily member 11,Osteoclast differentiation factor (ODF),Osteoprotegerin ligand,Receptor activator of nuclear factor kappa-B ligand,TNF-related activation-induced cytokine,TNFSF11,OPGL,CD254,TRANCE

价格 ￥1,700.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B0559
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Human

  • 分子别名

    Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor (ODF), Osteoprotegerin ligand, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TNFSF11, OPGL, CD254, TRANCE

  • Accession

    O14788

  • 克隆号

    S-SC009

  • 抗体类型

    Recombinant mAb

  • 抗体同种型

    IgG1,k

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 内毒素含量

    <1EU/mg

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4, containing no preservative

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    Blocking of RANKL signaling Functional assays

背景介绍

  • Denosumab is a human monoclonal antibody against RANKL used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.

  • ELISA

    • Immobilized RANK L/TNFSF11(182aa) Protein, Human(UA040336) can bind Denosumab. The EC50 for this effect is 0.9133 ng/mL.

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