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宿主来源
Rat抗原名称
CD3分子别名
T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain, CD247, Cd3z, Tcrz细胞定位
Cell membraneAccession
P24161克隆号
17A2抗体类型
Recombinant mAb抗体同种型
Rat IgG2b, κ应用
in vitro T cell stimulation/activation, FCM反应种属 ?
Ms纯化方式
Protein G浓度
Lot specific* (generally 0.5 to 5 mg/ml)*内毒素含量
＜1EU/mg标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, containing no preservative储存条件
2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.
| 应用 | 稀释度 |
|---|---|
| FCM | 1:500 |
This antibody recognizes the same epitope as clone 17A2.
The CD3 protein is a T-cell marker, a complex of four structurally distinct membrane glycoprotein isoforms, 20-50 kDa, comprising extracellular, transmembrane and intracellular domains. CD3 is associated with an heterodimer creating the T-cell receptor (TCR). The CD3 complex is responsible for mediating signal transduction to the internal environment upon antigenic recognition by TCR, causing T-cell proliferation and release of cytokines.
流式分析
Flow cytometric analysis of Mouse blood cells labelling CD3 antibody at 1/500 (0.1 μg) dilution/ (Red) compared with a Rat monoclonal IgG (Black) isotype control. Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody.
Flow cytometric analysis of Mouse splenocytes labelling CD3 antibody at 1/500 (0.1 μg) dilution/ (Red) compared with a Rat monoclonal IgG (Black) isotype control. Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody.
引用文献(1)
- A novel FTO-targeting nanodrug induces disulfidptosis and ameliorates the suppressive tumor immune environment to treat uveal melanoma
Hao Tian; Hongpei Deng; Xinlong Liu; Chang Liu; Chuan Zhang; Kam W. Leong; Jing Ruan; Xianqun Fan
Biomaterials. 2025 Feb 12 ; 0142-9612
影响因子： 12.8
货号：S0B0509产品名称：NA/LE Rat anti-mouse CD3 Recombinant mAb
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