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DR5 Recombinant Rabbit mAb (S-649-36)

Tumor necrosis factor receptor superfamily member 10B,Death receptor 5,TNF-related apoptosis-inducing ligand receptor 2 (TRAIL receptor 2,TRAIL-R2),CD262,TNFRSF10B,DR5,KILLER,TRAILR2,TRICK2,ZTNFR9

Datasheet COA

价格￥600.00 （供应商现货： 3-5个工作日）

货号 S0B0355

规格

25μl100μl1ml

数量

产品介绍

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产品规格

宿主来源

Rabbit
抗原名称

DR5
分子别名

Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL receptor 2; TRAIL-R2), CD262, TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
免疫原

Synthetic Peptide
细胞定位

Membrane
Accession

O14763
克隆号

S-649-36
抗体类型

Recombinant mAb
反应种属 ?

Hu
纯化方式

Protein A
浓度

0.5 mg/ml
标记

Unconjugated
性状

Liquid
缓冲体系

PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
储存条件

12 months from date of receipt / reconstitution, -20 °C as supplied
应用

WB

IP
稀释度

应用稀释度

WB 1:1000
IP 1:50

应用	稀释度
WB	1:1000
IP	1:50

背景介绍

DR5 is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Mice have a homologous gene, tnfrsf10b, that has been essential in the elucidation of the function of this gene in humans. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

免疫印迹
- WB result of DR5 Rabbit mAb
  Primary antibody: DR5 Rabbit mAb at 1/1000 dilution
  Lane 1: HeLa whole cell lysate 20 µg
  Lane 2: HepG2 whole cell lysate 20 µg
  Lane 3: HCT 116 whole cell lysate 20 µg
  Lane 4: HT-1080 whole cell lysate 20 µg
  Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
  Low expression control: HeLa whole cell lysate
  Predicted MW: 48 kDa
  Observed MW: 40, 48 kDa
免疫沉淀
- DR5 Rabbit mAb at 1/50 dilution (1 µg) immunoprecipitating DR5 in 0.4 mg HepG2 whole cell lysate.
  Western blot was performed on the immunoprecipitate using DR5 Rabbit mAb at 1/1000 dilution.
  Secondary antibody (HRP) for IP was used at 1/400 dilution.
  Lane 1: HepG2 whole cell lysate 20 µg (Input)
  Lane 2: DR5 Rabbit mAb IP in HepG2 whole cell lysate
  Lane 3: Rabbit monoclonal IgG IP in HepG2 whole cell lysate
  Predicted MW: 48 kDa
  Observed MW: 40, 48 kDa