NK1.1/CD161 Recombinant Rabbit mAb (S-428-32)
Killer cell lectin-like receptor subfamily B member 1C,CD161 antigen-like family member C,Lymphocyte antigen 55c (Ly-55c),NKR-P1.9,NKR-P1C,Natural killer cell surface protein P1-40 (NKR-P1 40),CD161c,Klrb1c
货号： S0B0328
- 价格： ￥600
- 规格：
- 数量：
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宿主来源
Rabbit抗原名称
NK1.1/CD161分子别名
Killer cell lectin-like receptor subfamily B member 1C, CD161 antigen-like family member C, Lymphocyte antigen 55c (Ly-55c), NKR-P1.9, NKR-P1C, Natural killer cell surface protein P1-40 (NKR-P1 40), CD161c, Klrb1c免疫原
Recombinant Protein细胞定位
MembraneAccession
P27814克隆号
S-428-32抗体类型
Recombinant mAb应用
FCM反应种属 ?
Ms纯化方式
Protein A浓度
0.5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 |
|---|---|
| FCM | 1:50 |
CD161 is a C-type lectin-like membrane receptor expressed at high levels on NK, NKT, Th17, Mucosa Associated Invariant T cells (MAITs), non-MAIT CD8+, tissue-resident memory cells (TRMs), αβ CD4+ T cells and CD8+ T cells. CD161 levels increase when αβ T cells enter tissues. The ligand for CD161 is the lectin-like transcript 1 (LLT1). CD161/LLT1 engagement inhibits NK cell function but can inhibit or enhance αβ T cell function depending on the co-stimulatory molecules involved. The inhibitory capacity of αβ T cells can be neutralized by blocking CD161. CD161 expression on γδ T cells is associated with enhanced IFN-γ and IL-17 production and enhanced endothelial transmigration.
流式分析
Flow cytometric analysis of Mouse splenocytes cells labelling NK1.1/CD161 antibody at 1/50 dilution (1 μg) (Right) compared with a Rabbit monoclonal IgG isotype control (Left). Goat Anti - Rabbit IgG Alexa Fluor® 488 was used as the secondary antibody. Cells were stained with rabbit IgG or NK1.1. Then stained with CD49b - PE. Gated on viable cells.
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