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CD38 Recombinant Rabbit mAb (Alexa Fluor® 594 Conjugate) (S-031-45-2)

2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1 (ADPRC 1),Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1),T10

价格 ￥1,056.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B0128
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 抗原名称

    CD38

  • 分子别名

    2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1 (ADPRC 1), Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1), T10

  • 免疫原

    Synthetic Peptide

  • 细胞定位

    Membrane

  • Accession

    P28907

  • 克隆号

    S-031-45-2

  • 抗体类型

    Rabbit mAb

  • 反应种属 ?

    Hu

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Alexa Fluor® 594

  • 性状

    Liquid

  • 缓冲体系

    PBS, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

  • 应用

    FCM

    ICC ?

  • 稀释度

    应用 稀释度
    FCM 1:2000
    ICC 1:200
    IF 1:200
背景介绍

  • CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.

  • 流式分析

    • Flow cytometric analysis of HeLa (Human cervix adenocarcinoma epithelial cell, left) / Ramos (Human Burkitt's lymphoma B lymphocyte, right) cells labelling CD38 (Alexa Fluor 594 Conjugate) antibody at 1/2000 (0.1 μg) dilution/ (red) compared with a Rabbit monoclonal IgG (Black) isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). Negative control: HeLa

  • 免疫细胞化学

    • ICC shows positive staining in Ramos cells. Anti-CD38 (Alexa Fluor® 594 Conjugate) antibody was used at 1/200 dilution (Red) and incubated overnight at 4°C. The cells were fixed with 4% PFA and permeabilized with 0.1% PBS-Triton X-100. Nuclei were counterstained with DAPI (Blue).

    • Negative control: ICC shows negative staining in HeLa cells. Anti-CD38 (Alexa Fluor® 594 Conjugate) antibody was used at 1/200 dilution and incubated overnight at 4°C. The cells were fixed with 4% PFA and permeabilized with 0.1% PBS-Triton X-100. Nuclei were counterstained with DAPI (Blue).

  • 免疫荧光

    • IF shows positive staining in paraffin-embedded human tonsil. Anti-CD38 (Alexa Fluor® 594 Conjugate) antibody was used at 1/200 dilution (Red) and incubated overnight at 4°C. Counterstained with DAPI (Blue). Heat mediated antigen retrieval with EDTA buffer pH9.0 was performed before commencing with IF staining protocol.

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