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Human TK-1, His tag

价格 600.00 供应商现货 : 3-5个工作日
货号 S0A9041
规格
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产品规格
  • 物种

    Human
  • Accession

    P04183
  • 表达序列

    Protein sequence (P04183, Ser2-Asn234, with C-10*His) SCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPANGGGGSHHHHHHHHHH

  • 表达宿主

    E.coli
  • 分子量

    Predicted MW: 27.2 kDa Observed MW: 26, 27 kDa
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <1EU/μg
  • 标签

    with C-10*His
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

背景介绍
  • Thymidine kinase 1, soluble (gene name TK1), is a human thymidine kinase. Two forms of this protein have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells. Thymidine kinase 1 has been shown to interact with P21. Elevations in serum TK-1 have been found to correlate with the return of breast and other forms of cancer. TK-1 can be used to detect cancer earlier, determine what stage it is in, and detect recurrence. Thymidine Kinase 1 can be measured based on its enzyme activity or using immunoassay.

  • 电泳

    • 2μg(R: reducing conditions)

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